Gene vs Protein homology
I am trying to find homologs for some proteins and I am wondering if it is better to find it by comparing the proteins or the coding genes or either is fine.
molecular-biology bioinformatics homology
asked 8 hours ago
Atajera
626
add a comment |
I am trying to find homologs for some proteins and I am wondering if it is better to find it by comparing the proteins or the coding genes or either is fine.
molecular-biology bioinformatics homology
asked 8 hours ago
Atajera
626
add a comment |
I am trying to find homologs for some proteins and I am wondering if it is better to find it by comparing the proteins or the coding genes or either is fine.
molecular-biology bioinformatics homology
asked 8 hours ago
Atajera
626
I am trying to find homologs for some proteins and I am wondering if it is better to find it by comparing the proteins or the coding genes or either is fine.
molecular-biology bioinformatics homology
molecular-biology bioinformatics homology
asked 8 hours ago
Atajera
626
asked 8 hours ago
Atajera
626
asked 8 hours ago
Atajera
626
asked 8 hours ago
Atajera
626
asked 8 hours ago
Atajera
626
626
add a comment |
add a comment |
1 Answer
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In most* scenarios you will probably want to look at a comparison of proteins following some additional matching that considers more than a single gene/protein. Luckily, this is a very common problem and one can often look up homologs through existing reference databases such as https://www.ncbi.nlm.nih.gov/homologene
Further, if genes are not present, their documentation will provide a good overview on ways to find homologs in other organisms.
*in some very special scenarios, gene sequences might be more suitable. For instance if one wanted to study similarity of non-coding regions of a gene. However these exceptions would seem beyond the general character of the question.
answered 6 hours ago
tsttst
1,130322
add a comment |
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1 Answer
1
active
oldest
votes
1 Answer
1
active
oldest
votes
active
oldest
votes
active
oldest
votes
In most* scenarios you will probably want to look at a comparison of proteins following some additional matching that considers more than a single gene/protein. Luckily, this is a very common problem and one can often look up homologs through existing reference databases such as https://www.ncbi.nlm.nih.gov/homologene
Further, if genes are not present, their documentation will provide a good overview on ways to find homologs in other organisms.
*in some very special scenarios, gene sequences might be more suitable. For instance if one wanted to study similarity of non-coding regions of a gene. However these exceptions would seem beyond the general character of the question.
answered 6 hours ago
tsttst
1,130322
add a comment |
In most* scenarios you will probably want to look at a comparison of proteins following some additional matching that considers more than a single gene/protein. Luckily, this is a very common problem and one can often look up homologs through existing reference databases such as https://www.ncbi.nlm.nih.gov/homologene
Further, if genes are not present, their documentation will provide a good overview on ways to find homologs in other organisms.
*in some very special scenarios, gene sequences might be more suitable. For instance if one wanted to study similarity of non-coding regions of a gene. However these exceptions would seem beyond the general character of the question.
answered 6 hours ago
tsttst
1,130322
add a comment |
In most* scenarios you will probably want to look at a comparison of proteins following some additional matching that considers more than a single gene/protein. Luckily, this is a very common problem and one can often look up homologs through existing reference databases such as https://www.ncbi.nlm.nih.gov/homologene
Further, if genes are not present, their documentation will provide a good overview on ways to find homologs in other organisms.
*in some very special scenarios, gene sequences might be more suitable. For instance if one wanted to study similarity of non-coding regions of a gene. However these exceptions would seem beyond the general character of the question.
answered 6 hours ago
tsttst
1,130322
In most* scenarios you will probably want to look at a comparison of proteins following some additional matching that considers more than a single gene/protein. Luckily, this is a very common problem and one can often look up homologs through existing reference databases such as https://www.ncbi.nlm.nih.gov/homologene
Further, if genes are not present, their documentation will provide a good overview on ways to find homologs in other organisms.
*in some very special scenarios, gene sequences might be more suitable. For instance if one wanted to study similarity of non-coding regions of a gene. However these exceptions would seem beyond the general character of the question.
answered 6 hours ago
tsttst
1,130322
answered 6 hours ago
tsttst
1,130322
answered 6 hours ago
tsttst
1,130322
answered 6 hours ago
tsttst
1,130322
1,130322
add a comment |
add a comment |
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